The magnolia bark has been used in traditional Chinese and Japanese healthcare for thousands of years. Scientific research on its properties began in the 1800s, but it was only recently that researchers isolated and identified its active ingredient, honokiol. Since then, many research studies have started worldwide. The historical uses of magnolia bark are very broad, with applications for supporting stable mood and promoting a healthy stress response being the most consistently recorded and validated. Recent research explores the potential of honokiol for promoting cellular health. Swanson's magnolia extract meets the standards set for scientific research.