Wallace has spent his summer in the lab breeding a strain of microscopic worms. He is four years into a biochemistry degree at a lakeside Midwestern university, a life that s a world away from his childhood in Alabama. His father died a few weeks ago, but Wallace didn t go back for the funeral, and he hasn t told his friends Miller, Yngve, Cole and Emma. For reasons of self-preservation, he has become used to keeping a wary distance even from those closest to him. But, over the course of one blustery end-of-summer weekend, the destruction of his work and a series of intense confrontations force Wallace to grapple with both the trauma of the past, and the question of the future.