The adaptogenic action of Rhodiola, as well as its protective properties for the heart, lungs, and central nervous system, are mainly due to its ability to affect the levels and action of monoamines and opioid peptides, such as β-endorphins.
Rhodiola's ability to help the body adapt to stress is possibly due to its property of increasing the levels of serotonin, dopamine, and other brain neurotransmitters.