Very powerful shampoo, definitely needs to be combined with conditioner. Even for my oily hair with fine strands. I didn't believe it at first, but it's necessary, especially when rinsing, it feels dry and it craves cream! As for hair loss, I have been extremely satisfied, around the 6-month mark I saw a huge difference and overall the quality of my hair has improved. It only requires a small amount in the hand and I alternate it with another, milder shampoo. Keep in mind that systems 5 and 6 are for highlights, while systems 3 and 4 are for regular colored hair.