Is a prophecy something definitive? Can free will overturn it? Do the stars foretell the future or only show a possible path to humans?

In the era of the Renaissance, in a small village in Calabria, the young peasant Giovanni Tratare dares to look into the eyes of the beautiful Elena, the granddaughter of the Doge of Venice. In order to win her heart, he leaves behind the small world of his everyday life and embarks on an adventurous journey. On his way, he escapes the stake of the witch Selene, and in return, she reveals to him everything that will happen in his tumultuous life: "Look, Giovanni, this is your tragic and glorious destiny. Do you accept it?"
Her words follow him throughout his wanderings, while the power of love leads him to the world of knowledge. From Florence and Venice to the monasteries of Mount Athos and Meteora, from Algiers and Jerusalem to Cyprus, wise teachers will initiate him into the secrets of philosophy and astrology, as well as the spiritual world of Christianity, Sufi teachings, and Kabbalah. At the same time, three women - the witch, the lover, and the wife - will help him, each in her own way, to explore the paths of the human soul.